Wilac D001
Weissella Confusa WIKIM51 (Wilac D001)
Wilac D001 Ingredient
Weissella confusa WIKIM51 Probiotic (Wilac D001)
- U.S. FDA NDI Registration for Weissella strain (NDI No. 1261)
- Individually Recognized Functional Ingredient No. 2026-6
A next-generation functional probiotic that has been scientifically validated for its body fat reduction effect and officially recognized as an individually approved functional ingredient by the Korean Ministry of Food and Drug Safety (MFDS).
This probiotic strain was originally isolated from traditional fermented wild dandelion kimchi from the clean southern coastal region of Korea.
Ingredient Name
Weissella confusa WIKIM51 Probiotic (Wilac D001)
Approval Number
No. 2026-6 (2026.02.09)
Functional Claim
May help reduce body fat.
Recommended Daily Intake
1x1010 CFU/day
Key Functional Benefits
Clinically Observed Effects
Human Clinical Trial Results
Key Functional Benefits
Clinically Observed Effects
Human Clinical Trial Results
Metabolic and Glycemic Improvements
Human Clinical Trial Results
Glycemic Control Benefits
The mechanism of blood glucose regulation was supported by three levels of evidence: cell study, animal study, and human clinical trial.
Changes in Gut Microbiota
Impact on Gut Microbiota Balance (LEfSe Analysis)
Changes in Gut Microbiota Normalization of Firmicutes/Bacteroidetes ratio.
• Normal Diet (ND): Dominance of 6 species including Lactobacillus murinus High-Fat Diet (HFD): *Increasedbeneficial bacteria : Desulfovibrio fairfieldensis, Enterorhabdus muris
*Decreased: Bacteroides sartorii, Muribaculum intestinale
After Wilac D001 intake:
-Significant changes observed in 6 species
-Bacteroides caecimuris: Negatively correlated with body weight, body fat, triglycerides, total cholesterol, blood glucose, and leptin
-Positively correlated with adiponectin
2. Wilac D001
• Associated with Improved gut microbiota composition altered by high-fat diet
Certifications, Awards & Presentations, Patents and Publications
Wilac D001- Certifications┃Awards & Presentations┃Patents┃Publications
Certifications
• MFDS Individually Approved Functional Ingredient (No. 2026-6)
• U.S. FDA NDI Registration for Weissella strain (NDI No. 1261)
• NET (New Excellent Technology) Certification from the Ministry of Trade, Industry and Energy (MOTIE), Korea
Patents
• Composition containing Weissella confusa WIKIM51 for anti-obesity activity (2018)
• Probiotic composition for improving women’s health (2021)
• Composition containing Wilac D001 strain for gut health improvement (2025)
Awards and Presentations
• ICOMES International Conference on Obesity and Metabolic Syndrome – Academic Presentation (2024)
• International Journal of Health Functional Food – Best Paper Award (2021)
• BioF Korea 2025 – Presentation on anti-obesity probiotic development (2025)
• Microbiological Society of Korea – Clinical results presentation on anti-obesity probiotics (2025)
Published Research
-
Journal
Title
Human clinical study
J. clinical medicine
Efficacy and safety of WCFA19(Weissella confusa WIKIM51) in reducing body fat in overweight and obese adults
In vivo
J. Functional Foods
Kimchi-derived probiotic intervention improve metabolic health in a sex-specific manner in rat offspring affected by maternal diet and postnatal nutrition
-
Microbiol Biotechnol Lett.
Modulation of lipogenesis and energy metabolism by the Weissella confusa WIKIM51 diet in a murine obesity model
-
Food Suppl Biomater Health.
Effects of Weissella confusa Wilac D001 Isolated from Dandelion Kimchi on Dextran Sulphate Sodium-Induced Colitis in Mice
In vitro
Applied sciences
The Antifungal Effect of Weissella confusa WIKIM51 (Wilac D001) on Vaginal Epithelial Cells Infected by Candida albicans
PHARMSVILLE | Tel. 02-553-1323 | Fax. 02-6952-7559 | E-mail :pharmsville@gmail.com
Head Office ㅣPharmsville B/D,37, Magokjungang8-ro 3-gil, Gangseo-gu, Seoul(07793) / CEO : Byungwook Lee / Business Registration No : 120-86-01608
Pharmsville Bio Lab | C-dong, 1st Floor, Unit 22, 26 Beobwon-ro 9-gil, Songpa-gu, Seoul (HBiz Park, Munjeong-dong)
Health Coach Biotechnology | Room 2015, Business Incubation Center, Natural Resources Research Center (Jeonnam Bioindustry Foundation), 50 Sandan 1-ro, Jangheung-eup, Jangheung-gun, Jeollanam-do
COPYRIGHT ©2016 PHARMSVILLE. ALL RIGHTS RESERVED